Category Archives: BCAN-NTRK1 Fusion

Inhibiting signaling in a BCAN-TRK1 brain tumor

This post only covers a small portion of a very in depth study of Peter Cook and coworkers of Memorial Sloan Kettering Cancer Center in New York City. The use of  CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) to introduce

BCAN-NTRK1 fusion in glioblastoma multiforme (GBM) patients

Kim and coworkers (2014) searched RNA-Seq data from 162 glioblastoma multiforme (GBM) patients in the Cancer Genome Altas. The goal was to find fusion genes that might be driving the cancer. The BCAN-NTRK1 was one of the potential driving mutations